Pathology

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Entry Category: Pathology - Starting with P

Pellagra

Pellagra is a form of malnutrition caused by a severe deficiency of niacin (also known as nicotinic acid or vitamin B3) in the diet. The disease affected thousands of Arkansans and other Southerners in the late nineteenth and early twentieth centuries. Symptoms of pellagra can include lack of energy, outbreaks of red splotches on the skin, diarrhea, and—in extreme cases—depression, dementia, and even death. Pellagra is not contagious, and the condition can be reversed. The lethargic appearance of pellagra victims was also a symptom of two other diseases widely found in the South at the time, hookworm and malaria. These three contributed to the false stereotype of Southerners at this time as lazy. Pellagra was first recognized as a disease in 1762 …

Pertussis

aka: Whooping Cough
Pertussis or “whooping cough” is an acute infectious disease caused by the bacteria Bordetella pertussis. Person-to-person transmission occurs through respiratory droplets. Following an incubation period of seven to fourteen days, pertussis progresses through the catarrhal, paroxysmal, and convalescent stages. Cold-like symptoms—including a runny nose, sneezing, a mild cough, and a low-grade fever—characterize the catarrhal stage. The paroxysmal stage begins one or two weeks later and lasts for up to eight weeks. Patients suffer from numerous rapid bursts of productive coughing followed by a long, inspiratory whoop, which is the origin of the disease’s common name. Young infants may exhibit breathing difficulties instead of whooping. Coughing spasms produce vomiting and cyanosis. Gradual recovery characterizes the convalescent stage. Neither vaccination nor recovery …

Polio

The poliovirus terrorized the United States for many years, and Arkansas was no exception. Infection with the virus either went unnoticed or caused poliomyelitis, commonly called polio, which resulted in paralysis that sometimes ended in death but more often left its victims permanently handicapped. As the disease often affected children, it was also called infantile paralysis. While the large urban centers of the country dealt with polio epidemics early in the twentieth century, Arkansas had only a few intermittent cases. The Arkansas Gazette, however, reported frequently on the disease, keeping its readers informed of efforts to combat, cure, and curtail its devastating effects in other areas. After the first significant numbers were reported in the state, Arkansans reacted to the …